| 1. | The other , called l - methionine , is a donor of methyl groups
另一个是l -甲硫氨酸，它可以提供甲基。 |
| 2. | Effect of s - adenosyl - l - methionine on growth and differentiation of hl - 60 cells
60细胞生长与分化的影响 |
| 3. | In nov . 2004 , a state - of - art l - methionine production facility with 350 tons capacity per annum was launched
2003年，新的注射级氨基酸精制生产车间建成并投入运行； 2004年11月，世界领先的年产350吨的甲硫氨酸生产车间建成并投入运行。 |
| 4. | This research is a part work of the " 863 " international project - " the technique of producing l - methionine by gene - engineering strain of immobilization cell "
本项研究是国家“ 863 ”中试项目“工程菌固定化细胞生产l ?蛋氨酸技术”的部分基础研究工作。 |
| 5. | S - adenosyl - l - methionine is an important metabolic intermediate in organism , which is involved in many biochemical reactions . its therapeuctic usage could be extensive and varied
S -腺苷甲硫氨酸( s - adenosyl - l - methionine ，简称sam或adomet )是生物体内重要的中间代谢物质，参与多种生化反应，具有广泛和多样的治疗作用。 |
| 6. | By contrast , l - methionine increased the level of methylation and thus reduced the expression of the gene in animals with loving mothers , and led to fear , anxiety and a heightened response to stress
与之相反， l -甲硫氨酸增加了甲基化水平，从而减弱了正常老鼠中糖皮质激素受体基因的表达，导致了恐惧、焦虑和对压力的强烈反应。 |
| 7. | Acetylornithine deacetylase is the key enzyme of producting l - methionine . we mainly do research work on the construction of acetylornithine deacetylase gene - engineering strain and characteristic of proteinase . in order to get high expression deacetylase strain , we obtain the gene by pcr arge gene . the product ( 2800bp ) was cloned into puc19 plasmid and confirmed with blue / white dot screening > restriction enzyme analysis and pcr . then taking the nucleotide sequencing compared with the sequence at blast of u . s . a . we constructed a high expression of gene - engineering strain - pxj 128 which containing the arge gene on the high expressing system of pxji18 with activity of acetylornithine deacetylase above 20000u / g
为了获得高效表达的脱乙酰鸟氨酸酶工程菌株，在工程菌技术改造及其固定化研究做了进一步的研究和探讨。我们采用基因工程技术，通过pcr技术扩增出了酰化酶关键酶基因?脱乙酰鸟氨酸酶基因arge ，将其克隆到puc19载体中，经酶切鉴定、 pcr鉴定筛选出重组阳性质粒，并测序鉴定，通过美国blast程序进行了基因数据库相似性比较分析。 |
| 8. | At mean time , we have studied on the characteristic of proteinase and make sure the suitable condition and influencing factor of deacetylase function . usin g the technology of immobiolized cell , the utlization of deacetylase have been increased deeply and lower production cost . the half deline period is more than 20 days and the production of l - methionine is above 75 %
采用固定化细胞技术，使酶的利用率得以大幅度提高，固定化细胞酶活的半衰期达20天以上，可连续拆分使用生产24天， l - met产率可达75以上。 |
