转录抑制 meaning in English
transcription inhibition
Examples
- These results indicated that aes might function as an antagonist of tle by binding with tle and inhibit the translocation of tle into nucleus
提示aes可能通过抑制tle进入胞核及形成四聚体而对tle的转录抑制功能起桔抗作用。 - These results indicated that molecules of tle family might play a role in gp130 signaling . the amino - terminal regions of aes and tle are highly homologous , both contains q ( glutamine ) domain
已知tle可通过q结构域形成四聚体,而且四聚体的形成对tle发挥转录抑制功能来说是必需的。 - It is show the mutant consists of a nuclei binding site and dna - binding domain is enough to negative regulation . a report plasmid pcat that we constructed has a cat gene expressed by a cmv early promoter
( 465 1079氨基酸段)对sv40启动子明显的抑制活性,因为它只包含dna结合域和核结合位点,说明发挥转录抑制功能的关键是ie180的dna结合域。 - The identified proteins are involved in a variety of cellular process including several zinc finger proteins relevant to transcription regulation , such as zinc finger 198 , 263 , 14 , 224 , zf6 , novel protein similar to transcriptional represser ctcf , and kruppel - like zinc finger protein ; two members of the adams ( a disintegrin and metalloprotease domain ) family ; two members of integrin family ; several proteins involved in the signal transduction , cell - cycle control , chromatin remodeling and transcription repression ; and also some proteins of cell skeleton and some with unknown functions
鉴定出的蛋白包括多个与转录调控相关的锌指蛋白,如锌指蛋白198 、 263 、 14 、 224 、 zf6 、转录抑制因子ctcf样蛋白、幻肚pple样锌指蛋白等:两个含金属蛋白酶结构域和整合素结合结构域的家族成员adam28和adam17 ;两个整合素家族成员pz整合素和含十个egf样结构域的整合素( tied ) ;与细胞信号转导通路有关的蛋白;与细胞周期调控有关的蛋白;与染色体重塑和基因转录抑制有关的蛋白;细胞骨架蛋白以及其他功能未明的蛋白等。