识别序列 meaning in English
eyecatcher
taq sequence
Examples
- Notch interaction with its ligands induces the cleavage of its intracellular domain ( ic ) , and the notch ic translocates to the nucleus and binds to rbp - j , the mammalian homolog of su ( h ) , to transactivate transcription of target genes such as e ( spl ) ( enhancer of split ) , hesl ( hairy and enhancer of split ) and hes5 four notch receptors and their ligands are differentially and redundantly expressed in a variety of vertebrate tissues
它通过其识别序列( cogtgggaa )结合于受调控基因的启动子区,在转录激活因子的驱动下调节细胞分化和个体发育相关基因的表达。在没有n 。 tch胞内段的情况下, rbpj可与包含sm盯( silencingmediatorforretlnoldandthyroidhormonereceptor )和组蛋白去乙酞化酶的转录辅助抑制复合物结合,当notch信号被激活时; rbpj可与n 。 - The two single - pass transmembrane proteins , delta and serrate , have been identified as notch ligands . the transcription factor suppressor of hairless [ su ( h ) ] is the major downstream effector of notch signaling pathway . rbp - j , the mammalian homolog of su ( h ) , recognizes the core sequence ( c / tgtgggaa ) of dna
Rbp - j是果蝇促神经发生基因su ( h ) ( suppressorofhairless )在哺乳动物的同源物,它通过其识别序列( c tgtgggaa )结合于受调控基因的启动子区,在转录激活因子的驱动下调节细胞分化和个体发育相关基因的表达。