莽草酸途径 meaning in English
shikimic acid pathway
Examples
- Shikimic acid pathway
莽草酸途径 - The epsp synthase is a necessary enzyme of the shikimate pathway and it is very conservative
Epsp合成酶是莽草酸途径的一个关键酶,其成熟蛋白在进化中极为保守。 - In microorganisms and plants the first step in the aromatic acid biosynthetic pathway is the condensation of pep and e4p , with the release of the phosphate of pep and the formation of dahp
在细菌和植物中,由公共途径莽草酸途径以及三个专一性途径分别合成苯丙氨酸、酪氨酸和色氨酸三种芳香族氨基酸。 - When both genes were co - expressed in e . coli , the activity of ppsa varied from 2 . 1 - 9 . 1 fold comparing to control , but the activity of tkta was relatively stable ( 3 . 9 - 4 . 5 fold ) . whatever the two genes were expressed respectively or cooperatively , both could promote the production of dahp , the first intermediate of the common aromatic pathway , but co - expression was more effective on forming dahp and screened ppt - and ptp - as more effective . the results demonstrate that co - expression of ppsa and tkta can improve the production of dahp , and what ' s more , when multigenes co - expressed , the recombinant which has coordinated enzymes activity is optimum
莽草酸途径的最优化和整体调控基因csra的敲除正是上述改变的分子基础,同时也为三种芳香族氨基酸的基因工程菌的构建打下了基础; 7 .在国内外首次实现了共同途径限制性底物关键酶ppsa刁无‘及arog与分支途径关键酶基因phea的串联高效表达,所构建的重组质粒ptga ,其ppsa 、 tkta 、 arog 、 cm和pd的酶活分别比对照提高了3 、 2 、 2 , 5 、 4 、 2 . 3倍,且其酶活比较协调一致; 8 .将ptga导入到筛选的基因敲除和基因替换菌株大肠杆菌31884 c甲b中,摇瓶发酵证实比以往所构建的基因工程菌株具有较高的phe产量和糖转化率率,分别为0 . 448 %和22 . 4 % 。 - The product chorismate of this pathway is precursor to the synthesis of the aromatic amino acids phenylalanine , tyrosine , and tryptophan as well as other essential aromatic secondary metabolites such as ubiquinone , menaquinone and vitamin k . phosphoenolpyruvate and shikimate 3 - phophate are converted to 5 - enolpyruvlshimimate - 3 - phosphate and phosphate
芳香族氨基酸苯丙氨酸、酪氨酸、色氨酸和其它一些必需代谢物如泛醌、维生素k2类、维生素k的起始物是莽草酸途径所产生的分枝酸。