自发突变 meaning in English
spontaneous mutation
Examples
- Spontaneous and induced mutation occur with animals viruses .
动物病毒的突变有自发突变和诱发突变。 - A few mutants were found on the plate containing nitrobenzene selective medium . their colony appearances have some difference from the wild strain . some evidences show that their growth characteristics on the selective medium are related to the plasmids harbored in their cells
对菌株的自发突变株的研究表明,这些菌株在硝基苯选择培养基上的生长特性是与它们细胞中所含质粒的特性相关的。 - In our laboratory , a unique mutation detection system using a shuttle vector plasmid has been established to demonstrate that a low concentration of mnng ( 0 . 2 m ) can induce nontargeted mutation in mammalian cells : the mammalian cells were exposed to 0 . 2m mnng for 2 . 5h , then a shuttle plasmid pz189 carrying supf trna gene was transfected into cells after 24h culture . we found a 5 - fold higher mutation frequency of the plasmid replicated in pretreated cells than the spontaneous mutation frequency of the plasmid replicated in control cells . this kind of mutation did not occur immediately after mnng exposure
我们实验室曾用一特殊的突变检测系统,直接证明dna损伤剂可在哺乳动物细胞诱发非定标性突变:首先用低浓度( 0 . 2 m )的短寿烷化剂mnng (半寿期为1 . 1hr )处理细胞2 . 5h后,继续培养24h ,将重组有用作突变检测的靶基因supftrna基因的穿梭质粒pz189转入细胞复制,发现在未受致癌物直接攻击的穿梭质粒中有较自发突变率高5倍以上的靶基因突变。