离子载体 meaning in English
ion carrier
ionophore
Examples
- Effects of cytokine combinations and calcium ionophore on differentiation of dendritic cells from acute myeloid leukemia cells
组合性细胞因子与钙离子载体诱导急性髓系白血病细胞向树突状细胞分化中的作用 - 2 . 18nm - agtx has no significant effect on calcium ionophore ionomycin stimulated ca2 + - dependent glu transmitter release . it is suggested that the inhibition result from the reduction of ca2 + influx but not the action on release machinery itself
18nm - agtx对钙离子载体ionimycin激发的钙依赖性glu递质释放没有明显的抑制作用，表明抑制效应可能源于对钙离子内流的阻断而不是作用于释放装置本身。 - It is interesting that pma plus calcium ionophore a23187 can inhibit pma - induced pta1 expression , and this effect ca n ' t be reversed by calcmeurin inhibiter fk506 . pta1 mabs can inhibit ctl activation and differentiation in mixed lymphocyte culture system when added at the beginning of the culture but can induce platelet activation and aggregation in the fc dependent manner . in 1997 , pta1 cdna was cloned from cdna library of tpa activated jurkat cells , which belongs to immunoglobulin superfamily ( igsf ) with two v - like domains of extracelluar region of pta1
Il - 2 、 tnf - 、 pma可以使t细胞pta1表达上调， tgf -可以下调pta1的表达，而pma加上钙离子载体a23187可以显著抑制pma的上调作用，且这种抑制作用不被calcineurin抑制剂fk506所逆转， 1997年burns教授从pma活化的jurkat细胞cdna文库中克隆了pta1cdna全长，证实pta1是一个新分子，属于免疫球蛋白超家族，胞膜外区有两个v样结构域。 - Furthermore , k + ionophore valinomycin and k + channel opener diazoxide alone induced neuronal apoptosis and caspase - 3 activation . besides , katp channel blockers tolbutamide and glybenclamide also showed neuroprotective effects and decreased caspase - 3 activation after hypoxia / reoxygenation . while the role of katp channels in neuronal apoptosis is not clear
为进一步证实钾通道在缺氧复氧诱导的神经元凋亡中的作用，我们采用了钾通道开通剂100pmdiazoxide及钾离子载体50nmvallnomycln 。