神经纤维缠结 meaning in English
nft neurofibrillary tangles
nfts
Examples
- In alzheimer s disease , the commonest form , the brain atrophies and abnormal proteins , called amyloid , accumlate in the brain substance , in the form of senile plaques
阿氏痴呆症的病变，是大脑的萎缩，大脑组织出现了不正常的淀粉样蛋白，称老年斑，或神经细胞结构产生变化，称神经纤维缠结。 - It may have a preventional function from alzheimer ' s disease . molecular biological studies are shown that apoe isoform has a isoform - specific role to neurodegeneration . apoe3 and apoei aid to sustain the stabilization of cytoskeleton protein tau , while apoe4hyperphosphorylates tau to destabilize the microtubule protein , which will make neurocyte easy to form neurofibrillary tangles in ad
分子生物学研究发现， apoe异构体对神经细胞退化表现出异构体特异作用， apoe _ 3和apoe _ 2有助于维持微管的稳定性，而apoe _ 4则使tau蛋白超磷酸化，破坏微管的稳定性，使神经细胞易于形成神经纤维缠结。