有丝分裂原 meaning in English
mitogen
Examples
- Mitogen activated protein kinase family
有丝分裂原激活蛋白质的激酶家族 - Furthermore , when normally induced 3t3 - l1 preadipocytes were treated with pd98059 ( an inhibitor of mek - 1 ) , to block the activation of erk1 and 2 , the mitotic clonal expansion was blocked , while adipocyte differentiation was not affected
我们用有丝分裂原激活蛋白激酶激酶（ mapkk / mek1 ）的抑制剂pd98059与诱导分化激素及药物一起对细胞诱导分化，克隆扩增不发生，但细胞分化未受影响。 - When the body suffered from malignancy , on the one hand , tumor restrained cell immunity function , antibody ' s production and the body ' s immunity effect through inducing restraining t cell , so it accelerated tumor ' s growth , on the other hand , tumor induced body fluid restrained gene , which prevented t cell and nk cell from killing tumor and restrained lymphocyte to mitotic multiplication reaction , indeed it accelerated tumor ' s growth
当机体一旦患上恶性肿瘤后，一方面肿瘤通过诱导抑制性t细胞，抑制细胞免疫功能及抗体的产生，抑制机体对肿瘤的免疫效应，从而使肿瘤逃逸机体的免疫监视，促进肿瘤的生长。另一方面，肿瘤通过诱导体液抑制因子阻止t细胞和nk细胞的等对肿瘤的杀伤作用，抑制淋巴细胞对有丝分裂原的增殖反应，甚至促进肿瘤的生长。 - On the other hand , the activity and function of p27 kip1 was affected by many physiological agents such as camp , il - 2 , rampamycin . the expression of p27kip1 increased after - irradiationin in the fibroblastoma cells , leading to arrest in gl phase , but its expression markedly decreased after y - irradiation in the nbcc cells , and leaded to arrest in g2 / m phase . several studies have reported that p27 kip1 involved in a much wider range of cellar processes , such as differentiation , apoptosis and migration , the expression level of p27kip1 is key for its function in dna damage responses
另一方面， p27kip ’的活性水平及功能作用，因细胞类型不同而各异，又受多种因素的影响，如一些有丝分裂原camp 、雷帕霉素可以上调p27kip ，的表达，而il一2等则与p27ki ” ‘的表达下降有关，受电离辐射( ir )照射的成纤维细胞瘤及用1 ， 25一二经基d3处理的hela细胞系在gl期均有游离的p27脚‘的积累，细胞周期阻滞在gl期;而在痣癌伽bccs )细胞中， y一射线能诱导p27吻‘表达水平的显著下调，细胞周期阻滞在g2舰期。