持续性痛 meaning in English

persistent ache
persistent pain

According to behavioral studies in adult rats , intrathecal administration of nociceptin , anandamide and win - 55 , 212 ( win - 2 ) ( cannabinoid receptor agonists ) produces an antinoceptive effect in versatile pain models including acute , tonic and chronic pain models ( see mogil & pasternak , 2001 ; pertwee , 2001 for review ) . thus , it could be concluded that nociceptin - orll receptor and anandamide - cannabinoid receptor systems constitute an important part of endogenous antinociceptive system . however , cellular mechanisms underlying the actions of orl1 and cannabinoid receptors on nociceptive information transmission in the spinal cord are still unknown
行为学研究也观察到鞘内注入nociceptin和大麻受体的激动剂如win55 , 212 - 2 ( win - 2 ) 、 anandamide等均可在多种痛模型上(包括急性痛、持续性痛和慢性痛模型等)产生明显的抗伤害性作用( seemogil pasternak , 2001 ; pertwee , 2001forreview ) ，由此可见nociceptin ?孤啡肽受体系统和anandamide ?大麻受体系统构成了内源性镇痛系统的重要组成部分。