抗原递呈 meaning in English
apc
Examples
- We used pbmc - derived dc loaded with apoptotic daudi cells , which were irradiated by 60co y after incubation with agonist cd40mab ( 5cl 1 , 5 ? g / ml ) for 24h
树突状细胞( dc )是体内功能最强的专职抗原递呈细胞，在机体免疫应答中起极其重要的作用。 - Tumor cell - derived exosomes containing tumor antigens and mhc class i molecule could present tumor antigens to dcs and induce cd8 + t cell - dependent antitumor immune responses significantly
其含有mhc类分子和lamp - 1 ，能够将肿瘤抗原呈递给抗原递呈细胞，产生显著的cd8 ~ + t细胞依赖的抗肿瘤免疫反应。 - Exosomes were characterized through sds - page , immunoblot analysis of protein markers such as immune molecules and observation in transient electron microscope . the cytokines were detected using elisa . we assessed the effect of hs - exo on dc maturation
在涉及抗原递呈的免疫分子中， hs一exo含有的mhc11类分子和cd86分子含量显著高于exo ; hs一exo含有的cd4o分子在exo中未检测到;两者均未检测到cd80分子。 - Dendritic cells ( dc ) , the initiator and modulator of immune response , are the most powerful professional antigen - presenting cells ( apc ) . recent studies indicated that dc have the most power to activate tumor specific ctl , therefore , dc are applied in the therapy of tumors , e
机体的抗肿瘤免疫主要为t淋巴细胞所介导， t细胞的致敏、激活、扩增和对肿瘤细胞的杀伤作用均有赖于抗原递呈细胞肿瘤递呈相应的抗原肽及相关因子的参与。 - Methods employed to prepare vaccine include rumor cells genetically modified with cytokines , costimulatory molecules and tumor antigenic peptides , dendritic cells ( dc ) primed with tumor antigens in vitro or genetically modified with tumor antigens , or fusion of tumor cells with antigen presenting cells ( apc )
现有的比较受到关注的制备肿瘤疫苗的方法有各种细胞因子、共刺激分子、肿瘤抗原肽等基因修饰的肿瘤细胞疫苗；体外抗原致敏的或肿瘤抗原肽基因修饰的树突状细胞疫苗；肿瘤细胞与抗原递呈细胞融合疫苗等。