慢性高血糖 meaning in English
chronic hyperglycemia
Examples
- The results suggested : the differential gene expression in the adrenal gland under acute hyperglycemia / hypoglycemia was related to blood glucose ; these genes might regulate blood glucose by influencing the metabolism and secretion of hormones , cytoskeleton constitution and signal transduction in the adrenal gland ; bbs4 gene might participate in glucoregulation via the activities of adrenal medulla ; the differential genes expressed under acute vs chronic hyperglycemia might play a basic role of the structural and functional changes in the adrenal gland , lead to the process of chronic complications of diabetes or accommodate to the status of hyperglycemia
结果提示：肾上腺基因差异性表达和血糖变化有关；在急性高低血糖情况下，这些基因可能通过影响肾上腺内激素的分泌和代谢、细胞骨架构成和信号转导来调节血糖； bbs4可能参与血糖调节，其作用可能和肾上腺髓质的活动有关；慢性高血糖情况下的肾上腺差异表达不同于急性高血糖，这种表达差异可能与肾上腺慢性的结构和机能改变相关，或参与了糖尿病慢性并发症的发生发展、高血糖状态的调节。 - The results indicated : 1 ) 521 genes up - regulated and 92 genes down - regulated under acute hyperglycemia , while 294 genes up - regulated and 464 down - regulated under acute hypoglycemia ; 1208 genes expressed differentially between acute hyperglycemia and hypoglycemia , including 94 genes expressed bi - directionally ; 2 ) bbs4 gene , which mainly expressed in the adrenal medulla , was up - regulated by hyperglycemia and down - regulated by hypoglycemia ; 3 ) 79 genes up - regulated and 43 down - regulated under chronic hypoglycemia , 725 genes expressed differentially between acute and chronic hyperglycemia , including 2 genes expressed bi - directionally
结果显示： ( 1 )在急性高血糖情况下有521个基因上调， 92个下调，急性低血糖情况下294个上调， 464个下调；差异表达的基因共1208个，其中双向性表达基因94个； ( 2 )在急性高低血糖情况下， bbs4基因呈双向性表达，原位杂交发现其主要表达在肾上腺髓质； ( 3 )慢性高血糖情况下， 79个基因上调， 43个下调，差异表达基因725个，其中双向性表达基因2个。 - To identify genes involving the regulation of blood glucose ( especially those to decrease blood glucose ) and genes related to the alteration in the morphology and function of the adrenal gland , to explore the molecular mechanisms of blood glucose regulation , we established the gene expression profiling of the monkey adrenal glands under acute hyperglycemia / hypoglycemia or chronic hyperglycemia with cdna microarray
为了遴选肾上腺中与血糖调节(尤其是降血糖的基因)以及慢性情况下肾上腺形态功能改变相关的基因，探究其在血糖调节中的分子机制。本实验以猕猴为实验对象，采用cdna微阵列技术，建立了急性高低血糖和慢性高血糖情况下肾上腺差异基因表达谱。