弗氏佐剂 meaning in English
freund's adjuvant
ifa
Examples
- Study on prevention of complete freunds adjuvant from stz - induced diabetes
完全弗氏佐剂预防自身免疫性糖尿病机理的初步研究 - Spantide prevents up - regulation of nitric oxide synthase expression and nitric oxide production in the spinal cord induced by fomaldehyde in rats
通过给大鼠右后足足跖部皮下注射完全弗氏佐剂 - C57bl / 6 ( h - 2b background ) mice were subcutaneously immunized with selected peptides in ifa ( incomplete freund ' s adjuvant ) respectively . 8 days later after immunization , spleens were removed to prepare splenocytes suspension
将这些肽片段分别与不完全弗氏佐剂制备成乳浊液，皮下注射免疫c57bl / 6小鼠， 8天后，处死小鼠，取出脾脏制备脾细胞悬液。 - This modification includes : ( 1 ) selecting two important molecules as candidates , ( 2 ) choosing a promiscuous t - cell epitope , and two b - cell epitopes or conserved amino acid sequences from the two important molecules , ( 3 ) connecting them adequately through analysis by the molecule designing software . therefore , the synthetic new antigen may interfere with the process of fertilization by multiple ways and its contraceptive effects may be enhancing . based on the molecule designing methods , the b - lymphocyte cell epitope of sperm / testis specific protein sp17 and cyritestin which interfere with fertilization in mouse , as well as the promiscuous th cell epitope of the ribonuclease ( rnase ) in bovine were selected
本研究以蛋白质分子设计的理论和方法研究避孕疫苗，将sp17和cyritestin关键表位和牛核糖核酸酶非选择性th细胞表位合理组合，获得新抗原- 35肽序列；并在合成、纯化后分别与弗氏佐剂、免疫刺激复合物( iscoms )混合后免疫不同遗传背景的雌性小鼠，观察血清和生殖道内的特异性抗体滴度的动态变化、生育力的改变以及免疫后小鼠重要脏器的组织病理学改变：以及在ivf下，新抗原的特异性抗血清对精卵相互作用的影响及抗原在精子表面的特异性定位。