始发症状 meaning in English

initial symptom

Often the illness develops slowly , with vague initial symptoms such as swelling of the hands , carpal tunnel syndrome , sensitivity to cold , fatigue , heartburn , difficulty swallowing , shortness of breath , and reduced endurance
硬皮病通常发展缓慢,伴随着不明原因的始发症状,如手部水肿,碗管综合症,对冷敏感,容易疲劳,心痛,吞咽困难,呼吸急促和身体耐受力的减退。
These immune and neural mechanisms may cause the initial symptoms of fatigue ; however , the fatigue symptom may be exacerbated by secondary overlapping factors ( e . g . depressive mood , sleep disturbances , unhealthy life style ) which are likely associated with the feeling of fatigue
这些免疫和神经机制可能引起疲劳的始发症状；但疲劳的症状可能会因续发的重叠因素（如情绪压抑，睡眠紊乱，不健康生活方式）而加重，它们可能与疲劳的感觉有关。