基因置换 meaning in English
gene substitution
Examples
- Prior to the vector construction , the availability of gene replacement was extensively tested in streptomyces . sp . fr - 008
在载体构建之前，我们先在链霉菌fr - 008中验证了基因置换方法的可行性。 - Such deficiencies cause lysosomal storage disorders , such as gaucher ' s disease , and replacement of the gene is an effective treatment
这样的缺陷引起溶酶体堆积病（例如，高歇病） ，基因置换是一种有效的疗法。 - 2kb or 7 . 2kb regions abolished the productivity of antibiotic fr - 008 . the expected strain after gene replacement in the region of 5 . 2kb have not been obtained for unknown reason
尽管由于未知的原因尚未获得5 . 2kb区域的基因置换菌株，但是以上的试验证明基因置换过程是可以在链霉菌fr - 008中进行的。 - Phz621 - phz622 , the new gene replacement vector system , had been constructed through the insertion of the 1 . 0kb and 1 . 4kb flanking sequences of hau3r gene from wild - type s . lividans in the same natural orientation
预期在携带有大插入片段的基因置换yac分子进入野生型变铅青链霉菌后， yac分子将通过1 . 4kb或1 - Lividans mutant strains la1 and la2 generated by gene replacement in dndb and dndc were obtained respectively . both of these two mutants lost dnd phenotype because of disruption of a respective dnd gene
首先利用基因置换实验获得分别在dndb 、 dndc基因内部发生基因中断的突变菌株la1利la2 ，并通过southern杂交进行了验证。