受体酪氨酸激酶 meaning in English
receptor tyrosine kinase
Examples
- Is pdgf tyrosine kinase inhibitor effective in pancreatic cancer
Pdgf受体酪氨酸激酶抑制剂在胰腺癌中是否有作用 - Gefitinib ( iressa , zd1839 ) , a specific tyrosine kinase inhibitor that targets the epidermal growth factor receptor ( egfr ) , is a novel molecular - targeting antineoplastic agent
摘要吉非替尼是一种新型的分子靶向抗癌药物，它选择性抑制表皮生长因子受体酪氨酸激酶而发挥作用。 - Sorafenib , a novel , oral multi - kinase inhibitor , targets on serine / threonine and receptor tyrosine kinases of the tumor cells and vasculature ; blocks the signal transconduction and inhibits tumor growth
摘要索拉非尼是首个口服多激酶抑制药，靶向作用于肿瘤细胞和肿瘤血管上的丝氨酸和（或）苏氨酸及受体酪氨酸激酶，阻断信号传导，抑制肿瘤生长。 - The neurotrophic and morphogenic activities of gdnf are mediated by its interaction with a multicomponent receptor complex formed by the ret receptor tyrosine kinase and a glycosylphosphatidylinositol ( gpi ) - anchored " accessory " receptor , gdnf family receptor alpha - 1 ( gfral )
Gdnf的神经营养作用主要是通过两类受体亚基介导，即胶质细胞源性神经营养因子受体alpha ( gfr s )亚基和受体酪氨酸激酶ret亚基。 - The members of src family are non - receptor tyrosine kinases . their make an important function in a complex network of intracellular signals , such as cell growth , proliferation , transformation , apoptosis , and cell adhesion , migration . the fact that src was discovered as an oncogene suggests that src could closely involvement in cancer
而今， src已发展成为包括九个成员在内的激酶家族，隶属于非受体酪氨酸激酶，是细胞信号转导途径中一类重要的信号分子，调控细胞的生长，增殖，凋亡，细胞黏附与迁移等一系列功能。