半寿期 meaning in English
half life
half period
half value period
half-life
Examples
- Our previous work identified delayed mutation occurred at target supf trna gene in plasmid transfected into cells pretreated with low concentration of alkylating agent n - methyl - n ' - nitro - n - nitrosoguanidine ( mnng )
在收回的质粒上我们检测到了延迟发生的、高于对照5倍以上的突变。由于w在细胞中的半寿期仅为1 - The quest continues for plasminogen activators with higher potency , specific thrombolytic activity , fibrin selectivity and longer half - life time . the recent progress in the protein engineering of plasminogen activators , including t - pa , u - pa , streptokinase , staphylokinase and other novel plasminogen activators , was presented in this article
一些pa突变体及新型溶栓剂,如k2p tnk - pa和star等的临床实验结果表明它们在延长体内半寿期增强对血纤维蛋白选择性和溶栓效率等方面有较大的改进。 - They can convert plasminogen into plasmin and thus degrade fibrin . despite the widespread use of established thrombolytic agents such as streptokinase , t - pa and u - pa , all these agents suffer from a number of inadequacies including resistance to reperfusion , occurrence of coronary reocclusion and bleeding complications
一些pa突变体及新型溶栓剂,如k2p tnk - pa和star等的临床实验结果表明它们在延长体内半寿期增强对血纤维蛋白选择性和溶栓效率等方面有较大的改进。 - In our laboratory , a unique mutation detection system using a shuttle vector plasmid has been established to demonstrate that a low concentration of mnng ( 0 . 2 m ) can induce nontargeted mutation in mammalian cells : the mammalian cells were exposed to 0 . 2m mnng for 2 . 5h , then a shuttle plasmid pz189 carrying supf trna gene was transfected into cells after 24h culture . we found a 5 - fold higher mutation frequency of the plasmid replicated in pretreated cells than the spontaneous mutation frequency of the plasmid replicated in control cells . this kind of mutation did not occur immediately after mnng exposure
我们实验室曾用一特殊的突变检测系统,直接证明dna损伤剂可在哺乳动物细胞诱发非定标性突变:首先用低浓度( 0 . 2 m )的短寿烷化剂mnng (半寿期为1 . 1hr )处理细胞2 . 5h后,继续培养24h ,将重组有用作突变检测的靶基因supftrna基因的穿梭质粒pz189转入细胞复制,发现在未受致癌物直接攻击的穿梭质粒中有较自发突变率高5倍以上的靶基因突变。