六聚体 meaning in English
hexamer
Examples
- In the last part of this thesis , the r - state human insulin hexamer has been selected as a target . a comparison has been made among the results obtained with fdsd simulation , md simulation and sd simulation
在论文的最后一部分，我们选择了r6态胰岛素六聚体这个较大的蛋白为研究对象，把fdsd模拟结果与md模拟和通常的真空sd模拟结果作了比较。 - In order to study the flexibility and stability of insulin hexamer in solution and the role of zn2 + and phenol , two 600 ps md simulations of the r - state human insulin hexamer system were carried out respectively
本论文用md模拟方法设计了两个对比计算机模拟实验，研究了r6态的胰岛素六聚体在水溶液中的稳定性和构象柔性，以及苯酚和锌离子对结构稳定性和构象柔性的影响。 - The md simulation data were analyzed in terms of average atomic positions , root mean square ( rms ) fluctuations , monomer - monomer interactions , hydrogen bond ( h - bond ) network , secondary structure , and so on . through the comparison , we found that when the system includes zn2 + ions and phenol , the stability of insulin hexamer is enhanced , but the conformational flexibility related to its biological activity is decreased . in addition , the insulin hexamer tends to dissociate in the absence of zn2 + and phenol
通过对这两个模拟所得到的轨迹在原子的平均位置、方均根涨落、方均根偏差、单体之间相互作用、氢键网络、二级结构等方面进行的比较分析发现，对于包含锌离子和苯酚的体系，胰岛素六聚体的稳定性得到了增强，但其构象柔性却受到了削弱；对不含锌离子和苯酚的体系，胰岛素六聚体的稳定性明显减弱，构象柔性却表现得较为突出，在这种情况下，胰岛素六聚体还表现出解聚的倾向。