一生坎坷 meaning in English

have bad [ill; hard; tough] luck all one's life; a lifetime of frustrations

How heavy was the karma from your past life that it effected such a pitiful fate as yours
是什么因果和前世业障弄得你一生坎坷？
On the occasion of the first anniversary of the silkair crash , he wrote this article to express his sense of sorrow and loss of a young lady whose life was so eventful yet colourful
际此胜安空难一周年纪念,杜教授特为文对这位一生坎坷,却又多姿多采的年青女子,表达心中的悲痛和惋惜。