vimentin meaning in English
波形蛋白
Examples
- Identification of vimentin in subline coc1 ddp by maldi - tof mass peptide map analysis
亚细胞中波形纤维蛋白的肽质谱指纹分析 - The temporal and spatial expression of gfap and vimentin of olfactory system of xenopus laevis during metamorphosis
变形期非洲爪蛙嗅觉系统胶质原纤维酸性蛋白和波形蛋白的时空表达 - Objective to study clinicopathologic features and to analyze differential of malignant mesothelioma . methods a case of malignant mesothelioma of the mediastinum was observed with pathologic examination and the literaturenas briefly reviewed . results the malignant mesothelioma showed biphasic forms , fibrous component and neoplastic cells arranged in stream - or nest - or cabinet - like forms , immumohistochemical staining showed that the neoplastic cells were positive for vimentin , desmin , nse , cd99 , cea , myod1 . conclusion malignant mesothelioma of mediastinum is a relatively rare poor prognosis , with the combination of clinical histopathological and immunohistochemical data , its correct diagnosis and differential diagnosis can be made
恶性间皮瘤发病率很低,大部分发生于胸膜和心包膜1 ,此瘤临床无特异性症状和体征,需与其他纵隔肿瘤相鉴别,方能作出正确诊断,现将1例纵隔恶性间皮瘤的临床病理资料报告如下,并结合文献对该肿瘤的形态结构特点、诊断与鉴别诊断、治疗与预后进行讨论。 - Vimentin is a kind of type iiiinterfilament and has high structural homogenity with c - fos , c - jun and creb . vimentin also modulates translocation of some signal molecule . whether vimentin is a downstream event of plc - 1 pathway and whether vimentin is an interchange site between plc - 1 pathway and other signal pathways needs further confirmation by molecular biology analysis such as yeast two - hybrid system and western blot
实验结果显示:经过egf刺激24小时后,相对于野生型mef组,敲除型mef组的2一de图谱中代表vimeniin的蛋白斑点消失,暗示缺失plc一y1基因可能直接或间接导致了vimentin的不表达, vimentin是否是plc一1通路的下游事件,以及是否是plc一yl通路与其他信号通路的交叉点,尚需结合其他方法进行深入研究。 - Correlation analysis was done using the % vol of matched spots from the two group , which is a useful function offered by the software . consequently , the correlation coefficients of the plc - 1 + / + group were 0 . 858 , 0 . 867 , 0 . 875 , yet the other were 0 . 842 , 0 . 846 , 0 . 863 . we cut out 7 bad - matched spots ( exist in one group and out of the other ) after analysis by auto matching and manual correction , three of which has been analyzed by pmf up to now . of the three analyzed , one has been idendified as vimentin definitely , while the other two can not be identified
经过软件分析和手工修正,挑取了7个在两组凝胶中不能匹配的蛋白质斑点(一组存在而另一组消失) ,目前已对其中3个进行了质谱鉴定,其中一个确切鉴定为vimentin ,而另外两个不能得到鉴定。 vimentin是一种第三类中间纤维,与c - fos 、 c - jun和creb具有较高的同源性,在细胞分裂时常常大量地重新组织,发生显著的磷酸化。