unmethylated meaning in English
未加甲醇的
未甲基化的
Examples
- This silencing also affects the function of many tumor suppressor genes , which , in their unmethylated state , put the brakes on uncontrolled cell growth
这种沉默也影响许多抑癌基因的功能,这些基因在非甲基化状态下可以阻止不受控制的细胞生长。 - The absence of the fmr1 gene product , fragile x mental retardation protein ( fmrp ) , is believed to be responsible for the typical physical and mental characteristics of the fragile x syndrome . alleles with between 43 and 200 cgg repeats are called permutation . they are generally unmethylated with normal transcript and protein level , but are extremely unstable during transmission to next generation
带有前突变( n = 43 200 )的个体其fmr1基因通常不会甲基化,可以正常转录和翻译产生fmrp ,故没有临床表型出现,但是,在向下一代传递的过程中却是非常不稳定的,会从前突变扩增成为全突变。