telomeric meaning in English

末端着丝粒的

Examples

2 . 4 affymetrix moe430a genechip analysis of expression pattern differences of undifferentiated escs and neural induced cells . 2 . 5 telomeric repeat ampliation protocol ( trap ) assays
2 . 4采用月升metrixmo以30a小鼠表达谱芯片进行未分化及分化后第4 、 10天细胞基因表达谱差异的分析。
We concluded that excessive expression of exogenous htr gene may compete with the endogenous telomerase rna and prevent rna template from combining with telomeric dna , thus repressing the elongation of telomeric dna ( telomeres ) and causing cell aging and cell death . - 6 - 3 . some modifications have been made to overcome the limitation of conventional telomeric repeat amplification protocol ( trap ) assay
分析其原因，可能是htr基因的过表达在数量和空间效应上同细胞内的端粒酶rna组分产生竟争，一定程度上阻碍了端粒酶rna模板区与端粒dna的结合，从而抑制端粒dna的延伸，导致细胞凋亡。
Telomerase is a ribonucleoprotein complex ( rnp ) composed by its rna component and protein subunits . telomerase can synthesize telomeric dna onto chromosomal ends using its own rna component as a template , elongate the length of telomere , increase cell life and even induce cell immortalization
端粒酶( telomerase )是由端粒酶rna和蛋白质组成的一种核糖核蛋白复合物( rnp ) 。端粒酶含有引物特异识别位点，能以自身rna为模板，逆转录合成端粒dna并加到染色体末端，使端粒延长，从而延长细胞的寿命甚至使其永生化。
Telomerase is a celler reverse transcriptase which catalyzes the synthesis and extension of telomeric dna . telomerase activation is not observed in normal tissues of somatic origin but in almost 90 % of human cancer , with the result the telomere shorten progressively with cell division and thus is a critical step for multistep carcinogenesis
正常人体细胞(非生殖细胞)中端粒酶活性的表达很低，或用目前的方法几乎检测不到，而在90以上的恶性肿瘤中可检测到端粒酶活性，相应的良性肿瘤则为阴性或仅有少数阳性。

telomeric meaning in English

Examples

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