tcdd meaning in English
戴奥辛
四氯二氧
Examples
- Effects of tcdd on the embryo lost at early pregnancy and survive rate at born
四氯苯二?哄对小鼠胚胎毒作用的研究 - The effects of tcdd on pregnant cynomolgus macaque macacafascicularis and its pregnancy outcome
对猕猴妊娠期及其妊娠结局的毒性影响 - There were many growth factors taking part in the control and regulation of metabolism within the bone development . 2 , 3 , 7 , 8 - tetrachlorodibenzo - p - dioxin ( tcdd ) is a widely spread environmental contaminant with extremely toxic effect
在骨发育过程中,激素调节、生长因子调节与神经系统共同形成了神经-内分泌-免疫-局部生长因子调节网络,参与骨发育的整个调节过程。 - The laboratory animal studies on tcdd and ra exposure indicated high incidences of congenital developmental malformations . in our previously study , we analyzed gene expression profile in igf gene family of tcdd - and ra - reduced fetal rats as well as cells and found antiestrogenic effect of tcdd and ra on igf genes
我们应用ra对不同发育时期的胎鼠进行诱导,构建骨骼发育畸形大鼠动物模型,研究遗传因素决定的先天畸形个体间对环境因素作用的易感性,阐明igfs家族成员在骨骼发育畸形大鼠中的作用。 - The insulin - like growth factor - 2 ( igf - 2 ) and igf conjugated protein - 6 ( igfbp - 6 ) mrna level in rat calvaria bone tissue and mc - 3t3 - el cells were detected by northern blotting analyses and reverse transcription polymerase chain reaction . the estrogen responsive element ( ere ) in igfbp - 6 gene promoter was identified and involved in tcdd - reduced regulation of the gene expression by electromobility shift assays ( emsa )
正常胎鼠头盖骨组织igf一2mrna呈高水平表达状态,而igfbp一6mrna的水平较低; ccf胎鼠头盖骨骨组织内igf一2mrna的表达较正常胎鼠降低, igfbp一6mrna的表达则明显升高; atra和e :联合应用时, atra可以抑制雌激素对细胞内igf一2和igfbp一6的这种调节作用。