prodrug meaning in English
前体药物
前药
潜药
药物前体
Examples
- Effects of glucagon - like peptide - 1 prodrug on glycemia control in non - diabetic mice
1对非糖尿病小鼠降糖作用的实验研究 - Mmf is the morpholinoethyl ester prodrug of its active metabolite inycophenolic acid ( mpa . mpa is a noncompetitive , reversible inhibitor of the enzyme inosine 5 ' - monophosphate dehydrogenase ( impdh ) , which plays a maor role in the de novo spohesis of guansine nucleotides
Balb c和c57bl 6小鼠是纯系的同种小鼠，具有不同的主要组织相容性抗原（ mhc i 、 11 ） ，可进行同种排斥反应的兔疫学研究。 - Abstract : aim to synthesize a new prodrug , resveratrol trinicotinate . methods in presence of lithium and a catalytic amount of naphthalene , the reaction of p - methoxybenzyl trimethylsilyl ether and 3 , 5 - dimethoxylbenzaldehyde gave resveratrol after a series of translation . resveratrol trinicotinate was obtained by the reaction of resveratrol and nicotinoyl chloride hydrochloride . results a mutual prodrug resveratrol trinicotinate was designed and synthesized . conclusion a novel method for synthesis of resveratrol and resveratrol trinicotinate has been afforded . the e - isomer is selectivily obtained by dehydration of the compound 2 with khso4
文摘:目的合成一种前药白藜芦醇烟酸酯.方法在金属锂片和催化量的萘的存在下, 3 , 5 -二甲氧基苯甲醛与对甲氧基苯甲醇的三甲基硅醚反应经过一系列转变得到白藜芦醇,白藜芦醇与烟酰氯反应得到白藜芦醇烟酸酯.结果设计并合成了白藜芦醇烟酸酯.结论提供了一种合成白藜芦醇及白藜芦醇烟酸酯的方法,采用khso4脱水可选择性的得到反式产物