nitrosoguanidine meaning in English
亚硝基胍
Examples
- Nitrosoguanidine crystallizes when the solution is cooled to 0℃ .
当萃取液冷却至0时，亚硝基胍结晶析出。 - Our previous work identified delayed mutation occurred at target supf trna gene in plasmid transfected into cells pretreated with low concentration of alkylating agent n - methyl - n ' - nitro - n - nitrosoguanidine ( mnng )
在收回的质粒上我们检测到了延迟发生的、高于对照5倍以上的突变。由于w在细胞中的半寿期仅为1 - Monofunctional alkylating agent n - methyl - n ' - nitro - n - nitrosoguanidine ( mnng ) is a widely spread environmental mutagen and carcinogen that targets dna and proteins to generate adducts . among the adducts , o6 - alkyl guanine is the predominant mutagenic lesion because of its mispairing properties , which can eventually lead to chromosomal aberrations , point mutations , and cell death . this lesion also appears to be involved in tumor initiation , particularly in gastric carcinogenesis
单功能烷化剂n -甲基- n -硝基- n -亚硝基胍( mnng )是一种在环境中广泛存在的化学诱变剂和致癌剂，它能和dna及蛋白质等生物大分子形成加合物( adduct ) ，其引起的与突变有关的主要dna损伤类型是o ~ 6 -甲基鸟嘌呤，这种损伤与肿瘤尤其是胃癌的发生密切相关。