mispairing meaning in English
错配 错配
误配
Examples
- Monofunctional alkylating agent n - methyl - n ' - nitro - n - nitrosoguanidine ( mnng ) is a widely spread environmental mutagen and carcinogen that targets dna and proteins to generate adducts . among the adducts , o6 - alkyl guanine is the predominant mutagenic lesion because of its mispairing properties , which can eventually lead to chromosomal aberrations , point mutations , and cell death . this lesion also appears to be involved in tumor initiation , particularly in gastric carcinogenesis
单功能烷化剂n -甲基- n -硝基- n -亚硝基胍( mnng )是一种在环境中广泛存在的化学诱变剂和致癌剂,它能和dna及蛋白质等生物大分子形成加合物( adduct ) ,其引起的与突变有关的主要dna损伤类型是o ~ 6 -甲基鸟嘌呤,这种损伤与肿瘤尤其是胃癌的发生密切相关。