kipl meaning in English

基普尔

The protein level of p21 increased lightly from 1 to3 h , then decreased at 6 - 9 h , reached maximum at 24 h after 2gy , it increased from 3 to 24 h exposed tology , and the protein level of p21 associated with cdk2 increased , which did not inhibit the cyclin e / cdk2 kinase activity , because of upregulation of cyclin e and deregulation of p27kipl after irradiation . in contrast to p21 , p27kipl may be a key regulator of cyclin e / cdk2 activity in dna damage responses . hi the ubiquitin - proteasome pathway invovled in regulation of p27kiplexpression in response to ir the ubiquitin - proteasome pathway regulated selective and time - controlled elimination of p27 kipl
与p27ki ” ，表达水平不同， pzi蛋白表达水平在zgy照射后略有增加， 6一gh略有下降，在照后24h达到最大; 10gy照后1一3h开始增加，持续到24h ，并且cycline / cdkz复合物中pzi蛋白结合增多，但cycline / cdkz激酶活性并未受到抑制，除了因ir诱导cydine蛋白表达水平增加外，另一重要的原因就是与pzi同一家族的p27kip ，蛋白表达水平下降，失去了对cycline / cdkz的抑制活性。