g蛋白偶联受体 meaning in English
g protein coupled receptor
g protein coupling receptors, gpcrs
g protein linked receptor
receptor coupled to g-protein
Examples
- Urotensin has been demonstrated to be the most potent mammalian vasoconstrictor
目前，研究已证实u的特异性受体为孤儿g蛋白偶联受体gpr14 。 - Stat proteins are activated by g - protein coupled receptors , while it has not been reported whether cck receptors , a kind of g - protein coupled receptors , can activate jak / stat pathway
Stat蛋白可被g蛋白偶联受体激活，而cck受体作为一种g蛋白偶联受体，是否对jak stat通路具有直接激活作用，尚未见报道。 - Hd biosciences co . , ltd has announced an important research collaboration with organon , the human health care business of akzo nobel . the agreement relates to the development by hd biosciences of functional assays for a number of identified g - protein coupled receptors and ion channels
根据这项协议，华大天源将为欧加农公司构建一系列的g蛋白偶联受体家族和离子通道家族的筛选模型，这些筛选模型均适应于高通量药物筛选。 - For example , the signal transduction of g protein - coupled receptor is mediated by g protein and can generate intracellular messages ; there exist some transmembrane proteins in the membrane of endoplasmic reticulum , and some of them are related with the synthesis and transportation of some proteins , while others are related with substance metablism , such as glucose - 6 - phosphatase ( g6pase ) . in addition , after binding with the 7 - tm receptors affiliated to frizzled protein family , wnt can activated disheveled protein in cytoplasm which is essential to embryonic development
如g蛋白偶联受体通过g蛋白介导产生胞内信使( camp ， cgmp ， dg ， ip _ 3 )将胞外信号传递到胞内，从而引起生物学效应；内质网上也存在着一些跨膜蛋白，其中一些与蛋白质的合成及运输有关，一些与物质代谢有关，如葡萄糖- 6 -磷酸酶。 - The extracellular 100pl ( ecl1 ) and ecl2 was linked by disulfide bond to maintenanced the stability of the protein secondary structure . in recent years , we showed that ccr5 as a co - receptor could interact with hiv - 1 infect ion . ccr5 was paid closed attention to since it was cloned in 1996 . the aim is to - obtain the sequence of first extracillular domain of 3 chemokine receptor 5 ( ccr5 ) n - terminal gene fragment with high level expression in e . coli and to prepare its specific antibody f ( ab ' ) ; , and its detected method
Ccr5具有g蛋白偶联受体家族( g - proteincoupledreceptors ， gpcrs )所特有的7个跨膜区( transmembrinedomains ， tm ) ，呈螺旋， tm的氨基酸有很高的保守性，膜外第一襻( extracellularloop1 ， ecl1 )和ecl2之间有二硫键相连，以维持蛋白质二级结构的稳定性。