brefeldin meaning in English
布雷菲（尔）德菌素
布雷菲德菌素
Examples
- It is known from studies using brefeldin a ( bfa ) that disruption of tgn can block the cytotoxicity of ricin , suggesting that the intracellular compartment may be an important part of the uptake pathway . ricin enters the cells by receptor - mediated endocytosis , followed by translocation across the membranes of intracellular organelles . in this study , a trans - golgi retention peptide signal yqrl was fused to the c - terminus of ricin a chain ( rta ) by polymerase chain reaction
本实验为重点研究反式高尔基体在毒素细胞内转运过程中的作用，我们设计了一个反式高尔基体的靶向信号肽基因yqrl ( tyr - gln - arg - leu )连接在rta分子的羧基端，用原核表达蛋白体系，纯化并测定rta - yqrl与rta蛋白对hela (人宫颈癌细胞) ， wish (人羊膜上皮细胞) ， skov - 3 (人卵巢癌细胞)三种细胞的毒性作用。