baclofen meaning in English
β-对氯苯基-γ-氨基丁酸
巴氯芬
贝可芬
氯苯氨丁酸
Examples
- Clinical observation of baclofen for treatment of postherpetic neuralgia
巴氯芬治疗带状疱疹感染后神经痛的临床观察 - Similarly , xenopus spinal growth cones turned away from a gradient of baclofen , an agonist of the gabab receptor
同样的， gabab受体的激动剂baclofen的浓度梯度也能够吸引或排斥爪蟾脊髓神经元的生长锥。 - Under normal culture conditions , pkc - dependent repulsion dominated , but the repulsion could be converted to attraction by inhibiting pkc or by elevating cytosolic cgmp
通常条件下， pkc通路介导了生长锥排斥反应，而ip3通路介导了吸引反应，由于pkc通路占据主导， sdf - 1和baclofen排斥生长锥。 - This response was mediated by gi and subsequent activation of phospholipase c ( plc ) , which triggered two pathways : protein kinase c ( pkc ) led to repulsion , and inositol 1 , 4 , 5 - triphosphate ( ip3 ) receptor activation led to attractive turning
信号转导机制的研究表明， sdf - 1和baclofen激活了生长锥表面的g蛋白耦联受体，通过gi将信号传递给plc ，进而激活pkc和ip3信号通路。