a链 meaning in English
a chain
Examples
- Ricin is a heterodimeric rip comprised of a and b chains joined through a disulfide bond
A链( rta )是活性链，分子量约32kd ，第十位残基asn连接一条寡糖链。 - Our goal is to express the ricin a chain ( rta ) and its modification rta - kdel ( er - retrival signal ) in escherichia coli
本论文旨在研究蓖麻毒素a链蛋白( rta )及其修饰体rta - kdel (内质网保留信号肽)在大肠杆菌中的表达。 - Ricin b chain ( rtb ) can specifically recognize receptors on the cell membrane , which have a terminal galactose . rtb is responsible for the binding to the cell receptors and may facilitate the translocation of rta
B链具有凝集素活性，其本身几乎没有毒性，主要作用就是识别和结合细胞表面末端含有半乳糖基结构的受体，并协助a链进入细胞内。 - Ricin toxin has wide - range anti - tumor spectrum . however , because rta has no selectivity , it can damge normal ce lls too . these years , ricin and it ' s a chain ( rta ) have been used to conjugate with monoclonal antibody to prepare immunotoxins ( its )
近年来，蓖麻毒a链可以与单克隆抗体相交联而制备免疫毒素( immunotoxin ， it ) ，免疫毒素既具有强大的肿瘤杀伤作用，同时又有抗体的特异性，可以将毒素分子靶向运送到肿瘤细胞，以减少对正常细胞的损伤。 - Because expressed in escherichia coli , ricin a chain is not degraded easily for its non - glycosylation . our experiments lay a foundation for the researches that rta conjugates a monoclonal antibody to synthesize immunotoxins and the immunotoxins are used for cancer - targeted therapy
蓖麻毒素a链在大肠杆菌中表达，因无糖基化修饰，克服了进入体内后被迅速降解的缺点，为进一步与单链抗体基因嵌合表达形成单链免疫毒素，对肿瘤细胞进行导向治疗研究奠定基础。